BDBM50505813 CHEMBL4580951

SMILES: COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(C)cc(C)c1

InChI Key: InChIKey=USEVLZOURVEHSL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505813   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505813 (CHEMBL4580951) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(C)cc(C)c1 Show InChI InChI=1S/C23H24N2O2S/c1-15-12-16(2)14-18(13-15)24-23(26)25-10-8-21-20(9-11-28-21)22(25)17-4-6-19(27-3)7-5-17/h4-7,9,11-14,22H,8,10H2,1-3H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382
					More data for this Ligand-Target Pair