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BDBM50505814 CHEMBL4458027

SMILES: NC(=O)c1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=QRMNWAFKNMZJQT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505814   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lutropin-choriogonadotropic hormone receptor


(Homo sapiens (Human))		BDBM50505814
PNG
(CHEMBL4458027)
Show SMILES NC(=O)c1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C21H17Cl2N3O2S/c22-14-9-15(23)11-16(10-14)25-21(28)26-7-5-18-17(6-8-29-18)19(26)12-1-3-13(4-2-12)20(24)27/h1-4,6,8-11,19H,5,7H2,(H2,24,27)(H,25,28)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.65E+4n/an/an/an/an/an/a



Bayer AG

Curated by ChEMBL


Assay Description
Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...

J Med Chem 62: 10321-10341 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01382
More data for this
Ligand-Target Pair