BDBM50505816 CHEMBL4573451

SMILES: Clc1cc(Cl)cc(NC(=O)N2CCc3sccc3C2c2ccncc2)c1

InChI Key: InChIKey=RFTDOKATMJAJBE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505816 (CHEMBL4573451) Show SMILES Clc1cc(Cl)cc(NC(=O)N2CCc3sccc3C2c2ccncc2)c1 Show InChI InChI=1S/C19H15Cl2N3OS/c20-13-9-14(21)11-15(10-13)23-19(25)24-7-3-17-16(4-8-26-17)18(24)12-1-5-22-6-2-12/h1-2,4-6,8-11,18H,3,7H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382
					More data for this Ligand-Target Pair