BDBM50507331 CHEMBL3923136

SMILES: [H][C@]1(CN=C(O)C11CCN(CCNC(=O)c2cnc3ccccc3c2)CC1)c1ccc(F)cc1

InChI Key: InChIKey=BAHMBPJZGYBLIO-QFIPXVFZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50507331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D2 (PLD2) (Homo sapiens (Human))	BDBM50507331 (CHEMBL3923136) Show SMILES [H][C@]1(CN=C(O)C11CCN(CCNC(=O)c2cnc3ccccc3c2)CC1)c1ccc(F)cc1 |r,t:3| Show InChI InChI=1S/C26H27FN4O2/c27-21-7-5-18(6-8-21)22-17-30-25(33)26(22)9-12-31(13-10-26)14-11-28-24(32)20-15-19-3-1-2-4-23(19)29-16-20/h1-8,15-16,22H,9-14,17H2,(H,28,32)(H,30,33)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of GFP-fused PLD2 (unknown origin) expressed in HEK293 cells by cellular assay				Bioorg Med Chem Lett 28: 3670-3673 (2018) Article DOI: 10.1016/j.bmcl.2018.10.033
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM50507331 (CHEMBL3923136) Show SMILES [H][C@]1(CN=C(O)C11CCN(CCNC(=O)c2cnc3ccccc3c2)CC1)c1ccc(F)cc1 |r,t:3| Show InChI InChI=1S/C26H27FN4O2/c27-21-7-5-18(6-8-21)22-17-30-25(33)26(22)9-12-31(13-10-26)14-11-28-24(32)20-15-19-3-1-2-4-23(19)29-16-20/h1-8,15-16,22H,9-14,17H2,(H,28,32)(H,30,33)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of PLD1 in human Calu1 cells				Bioorg Med Chem Lett 28: 3670-3673 (2018) Article DOI: 10.1016/j.bmcl.2018.10.033
					More data for this Ligand-Target Pair