null

SMILES: NS(=O)(=O)c1ccc(cc1)C(=O)N1CCC(O)(CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=LIUBLVAZYHNOIY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50507834   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50507834 (CHEMBL4442611) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H19ClN2O4S/c19-15-5-3-14(4-6-15)18(23)9-11-21(12-10-18)17(22)13-1-7-16(8-2-13)26(20,24)25/h1-8,23H,9-12H2,(H2,20,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...				Eur J Med Chem 163: 443-452 (2019) Article DOI: 10.1016/j.ejmech.2018.11.073
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50507834 (CHEMBL4442611) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H19ClN2O4S/c19-15-5-3-14(4-6-15)18(23)9-11-21(12-10-18)17(22)13-1-7-16(8-2-13)26(20,24)25/h1-8,23H,9-12H2,(H2,20,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of recombinant full length human carbonic anhydrase-7 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...				Eur J Med Chem 163: 443-452 (2019) Article DOI: 10.1016/j.ejmech.2018.11.073
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50507834 (CHEMBL4442611) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H19ClN2O4S/c19-15-5-3-14(4-6-15)18(23)9-11-21(12-10-18)17(22)13-1-7-16(8-2-13)26(20,24)25/h1-8,23H,9-12H2,(H2,20,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of recombinant full length human carbonic anhydrase-1 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...				Eur J Med Chem 163: 443-452 (2019) Article DOI: 10.1016/j.ejmech.2018.11.073
					More data for this Ligand-Target Pair
Carbonic anhydrase 14 (Homo sapiens (Human))	BDBM50507834 (CHEMBL4442611) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H19ClN2O4S/c19-15-5-3-14(4-6-15)18(23)9-11-21(12-10-18)17(22)13-1-7-16(8-2-13)26(20,24)25/h1-8,23H,9-12H2,(H2,20,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-14 catalytic domain assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped flow ...				Eur J Med Chem 163: 443-452 (2019) Article DOI: 10.1016/j.ejmech.2018.11.073
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50507834 (CHEMBL4442611) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H19ClN2O4S/c19-15-5-3-14(4-6-15)18(23)9-11-21(12-10-18)17(22)13-1-7-16(8-2-13)26(20,24)25/h1-8,23H,9-12H2,(H2,20,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-12 catalytic domain assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped flow ...				Eur J Med Chem 163: 443-452 (2019) Article DOI: 10.1016/j.ejmech.2018.11.073
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50507834 (CHEMBL4442611) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H19ClN2O4S/c19-15-5-3-14(4-6-15)18(23)9-11-21(12-10-18)17(22)13-1-7-16(8-2-13)26(20,24)25/h1-8,23H,9-12H2,(H2,20,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-9 catalytic domain assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped flow a...				Eur J Med Chem 163: 443-452 (2019) Article DOI: 10.1016/j.ejmech.2018.11.073
					More data for this Ligand-Target Pair