BDBM50507848 CHEMBL4457824

SMILES: CC(C)c1ccc2[nH]c(nc2c1)[C@@H](N)[C@@H](C)O

InChI Key: InChIKey=DGHNWZJTTIQFIJ-PELKAZGASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50507848   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel alpha subunit (Homo sapiens (Human))	BDBM50507848 (CHEMBL4457824) Show SMILES CC(C)c1ccc2[nH]c(nc2c1)[C@@H](N)[C@@H](C)O |r| Show InChI InChI=1S/C13H19N3O/c1-7(2)9-4-5-10-11(6-9)16-13(15-10)12(14)8(3)17/h4-8,12,17H,14H2,1-3H3,(H,15,16)/t8-,12+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 27: 230-239 (2019) Article DOI: 10.1016/j.bmc.2018.12.002
					More data for this Ligand-Target Pair