BDBM50508363 CHEMBL4588098

SMILES: Fc1cccc(-c2ccc(o2)C(=O)N2CCN(Cc3ccc(OC4CCNCC4)c(Cl)c3)CC2)c1F

InChI Key: InChIKey=NOMMHCFIHLAUAZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50508363 (CHEMBL4588098) Show SMILES Fc1cccc(-c2ccc(o2)C(=O)N2CCN(Cc3ccc(OC4CCNCC4)c(Cl)c3)CC2)c1F Show InChI InChI=1S/C27H28ClF2N3O3/c28-21-16-18(4-5-24(21)35-19-8-10-31-11-9-19)17-32-12-14-33(15-13-32)27(34)25-7-6-23(36-25)20-2-1-3-22(29)26(20)30/h1-7,16,19,31H,8-15,17H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of Eu-labelled UT2 from recombinant human UT2 receptor expressed in HEK293 cell membranes preincubated for 10 mins followed by Eu-labell...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058
					More data for this Ligand-Target Pair
Urotensin II receptor (Homo sapiens (Human))	BDBM50508363 (CHEMBL4588098) Show SMILES Fc1cccc(-c2ccc(o2)C(=O)N2CCN(Cc3ccc(OC4CCNCC4)c(Cl)c3)CC2)c1F Show InChI InChI=1S/C27H28ClF2N3O3/c28-21-16-18(4-5-24(21)35-19-8-10-31-11-9-19)17-32-12-14-33(15-13-32)27(34)25-7-6-23(36-25)20-2-1-3-22(29)26(20)30/h1-7,16,19,31H,8-15,17H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Antagonist activity at human UT2 receptor expressed in HEK293-aeq cells assessed as inhibition of U2-induced intracellular calcium mobilization prein...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058
					More data for this Ligand-Target Pair