null

SMILES: [H][C@@]12CC=C(C)[C@@]([H])(C1)[C@]([H])(NC2(C)C)c1ccnc2ccccc12

InChI Key: InChIKey=HQDLJJQZMYAAPU-LSBZLQRGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50508933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50508933 (CHEMBL4461511) Show SMILES [H][C@@]12CC=C(C)[C@@]([H])(C1)[C@]([H])(NC2(C)C)c1ccnc2ccccc12 |r,t:3| Show InChI InChI=1S/C20H24N2/c1-13-8-9-14-12-17(13)19(22-20(14,2)3)16-10-11-21-18-7-5-4-6-15(16)18/h4-8,10-11,14,17,19,22H,9,12H2,1-3H3/t14-,17-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
American University of Health Sciences Curated by ChEMBL					Assay Description Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...				J Nat Prod 82: 1953-1960 (2019) Article DOI: 10.1021/acs.jnatprod.9b00314
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50508933 (CHEMBL4461511) Show SMILES [H][C@@]12CC=C(C)[C@@]([H])(C1)[C@]([H])(NC2(C)C)c1ccnc2ccccc12 |r,t:3| Show InChI InChI=1S/C20H24N2/c1-13-8-9-14-12-17(13)19(22-20(14,2)3)16-10-11-21-18-7-5-4-6-15(16)18/h4-8,10-11,14,17,19,22H,9,12H2,1-3H3/t14-,17-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
American University of Health Sciences Curated by ChEMBL					Assay Description Antagonist activity at human AChR alpha7 transfected in rat GH3 cells assessed as decrease in epibatidine-induced calcium influx incubated for 1 hr b...				J Nat Prod 82: 1953-1960 (2019) Article DOI: 10.1021/acs.jnatprod.9b00314
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM50508933 (CHEMBL4461511) Show SMILES [H][C@@]12CC=C(C)[C@@]([H])(C1)[C@]([H])(NC2(C)C)c1ccnc2ccccc12 |r,t:3| Show InChI InChI=1S/C20H24N2/c1-13-8-9-14-12-17(13)19(22-20(14,2)3)16-10-11-21-18-7-5-4-6-15(16)18/h4-8,10-11,14,17,19,22H,9,12H2,1-3H3/t14-,17-,19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
American University of Health Sciences Curated by ChEMBL					Assay Description Antagonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...				J Nat Prod 82: 1953-1960 (2019) Article DOI: 10.1021/acs.jnatprod.9b00314
					More data for this Ligand-Target Pair