BDBM50509840 CHEMBL4528294

SMILES: CCN(CC)C(=O)Oc1ccc(cc1)C(=O)Nc1cccc(CCNS(=O)(=O)c2ccccc2)c1

InChI Key: InChIKey=CKNUMYCNJNXQFL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50509840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50509840 (CHEMBL4528294) Show SMILES CCN(CC)C(=O)Oc1ccc(cc1)C(=O)Nc1cccc(CCNS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C26H29N3O5S/c1-3-29(4-2)26(31)34-23-15-13-21(14-16-23)25(30)28-22-10-8-9-20(19-22)17-18-27-35(32,33)24-11-6-5-7-12-24/h5-16,19,27H,3-4,17-18H2,1-2H3,(H,28,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...				ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50509840 (CHEMBL4528294) Show SMILES CCN(CC)C(=O)Oc1ccc(cc1)C(=O)Nc1cccc(CCNS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C26H29N3O5S/c1-3-29(4-2)26(31)34-23-15-13-21(14-16-23)25(30)28-22-10-8-9-20(19-22)17-18-27-35(32,33)24-11-6-5-7-12-24/h5-16,19,27H,3-4,17-18H2,1-2H3,(H,28,30)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2B expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...				ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395
					More data for this Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50509840 (CHEMBL4528294) Show SMILES CCN(CC)C(=O)Oc1ccc(cc1)C(=O)Nc1cccc(CCNS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C26H29N3O5S/c1-3-29(4-2)26(31)34-23-15-13-21(14-16-23)25(30)28-22-10-8-9-20(19-22)17-18-27-35(32,33)24-11-6-5-7-12-24/h5-16,19,27H,3-4,17-18H2,1-2H3,(H,28,30)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...				ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395
					More data for this Ligand-Target Pair