BDBM50509976 CHEMBL4448243

SMILES: COc1cccc(Nc2ncc3CSc4ncccc4-c3n2)c1

InChI Key: InChIKey=PWHVTWWBTYNMCF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50509976   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50509976 (CHEMBL4448243) Show SMILES COc1cccc(Nc2ncc3CSc4ncccc4-c3n2)c1 Show InChI InChI=1S/C17H14N4OS/c1-22-13-5-2-4-12(8-13)20-17-19-9-11-10-23-16-14(15(11)21-17)6-3-7-18-16/h2-9H,10H2,1H3,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of recombinant human KDR incubated for 1 hr using Tyr1 substrate by fluorimetry based Z'-LYTE-Tyr1 Peptide assay				ACS Med Chem Lett 10: 457-462 (2019) Article DOI: 10.1021/acsmedchemlett.8b00499
					More data for this Ligand-Target Pair