BDBM50509979 CHEMBL4441332

SMILES: C1Sc2ncccc2-c2nc(Nc3ccccc3)ncc12

InChI Key: InChIKey=LOZAIWVTPZWCJY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50509979   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50509979 (CHEMBL4441332) Show SMILES C1Sc2ncccc2-c2nc(Nc3ccccc3)ncc12 Show InChI InChI=1S/C16H12N4S/c1-2-5-12(6-3-1)19-16-18-9-11-10-21-15-13(14(11)20-16)7-4-8-17-15/h1-9H,10H2,(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of recombinant human KDR incubated for 1 hr using Tyr1 substrate by fluorimetry based Z'-LYTE-Tyr1 Peptide assay				ACS Med Chem Lett 10: 457-462 (2019) Article DOI: 10.1021/acsmedchemlett.8b00499
					More data for this Ligand-Target Pair