BDBM50510402 CHEMBL4456947

SMILES: CN1CCc2c(C1)sc1ncnc(Nc3ccc(F)cc3Br)c21

InChI Key: InChIKey=HYUVLLIEYCTCFT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50510402   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50510402 (CHEMBL4456947) Show SMILES CN1CCc2c(C1)sc1ncnc(Nc3ccc(F)cc3Br)c21 Show InChI InChI=1S/C16H14BrFN4S/c1-22-5-4-10-13(7-22)23-16-14(10)15(19-8-20-16)21-12-3-2-9(18)6-11(12)17/h2-3,6,8H,4-5,7H2,1H3,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chengdu Medical College Curated by ChEMBL					Assay Description Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay				Bioorg Med Chem 27: 2268-2279 (2019) Article DOI: 10.1016/j.bmc.2019.04.022
					More data for this Ligand-Target Pair