BDBM50510994 CHEMBL4521016
SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(O[C@@H]3CCOC3)cc2)c1
InChI Key: InChIKey=OBWASQILIWPZMG-VUOLKEHKSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50510994 (CHEMBL4521016) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jamia Hamdard Curated by ChEMBL | Assay Description Inhibition of human SGLT1 | Eur J Med Chem 184: (2019) Article DOI: 10.1016/j.ejmech.2019.111773 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50510994 (CHEMBL4521016) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Jamia Hamdard Curated by ChEMBL | Assay Description Inhibition of human SGLT2 | Eur J Med Chem 184: (2019) Article DOI: 10.1016/j.ejmech.2019.111773 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50510994 (CHEMBL4521016) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Jamia Hamdard Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed i HEK293 cell membranes assessed as reduction in [14C]-alpha-methyl glucopyranoside uptake incubated for 4 hrs by... | Eur J Med Chem 184: (2019) Article DOI: 10.1016/j.ejmech.2019.111773 | |||||||||||
More data for this Ligand-Target Pair |