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BDBM50511433 CHEMBL4470452

SMILES: CNc1cc(nc(N)n1)-c1cccc(C)c1C

InChI Key: InChIKey=WCJDHMSUZXVPCK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50511433   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
7,8-dihydro-8-oxoguanine triphosphatase


(Homo sapiens (Human))		BDBM50511433
PNG
(CHEMBL4470452)
Show SMILES CNc1cc(nc(N)n1)-c1cccc(C)c1C
Show InChI InChI=1S/C13H16N4/c1-8-5-4-6-10(9(8)2)11-7-12(15-3)17-13(14)16-11/h4-7H,1-3H3,(H3,14,15,16,17)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.20n/an/an/an/an/an/a



Gilead Sciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...

ACS Med Chem Lett 11: 358-364 (2020)


Article DOI: 10.1021/acsmedchemlett.9b00420
More data for this
Ligand-Target Pair