BDBM50511439 CHEMBL4565830
SMILES: CNc1cc(nc(N)n1)N1CCCCC1
InChI Key: InChIKey=WOSMHMANFDUDQJ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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7,8-dihydro-8-oxoguanine triphosphatase (Homo sapiens (Human)) | BDBM50511439 (CHEMBL4565830) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo... | ACS Med Chem Lett 11: 358-364 (2020) Article DOI: 10.1021/acsmedchemlett.9b00420 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |