BDBM50511445 CHEMBL4568781

SMILES: Cc1cc(-c2cccc(Cl)c2Cl)c2nc(N)[nH]c2c1

InChI Key: InChIKey=RPTCZMDHFOOKHF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50511445   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
7,8-dihydro-8-oxoguanine triphosphatase (Homo sapiens (Human))	BDBM50511445 (CHEMBL4568781) Show SMILES Cc1cc(-c2cccc(Cl)c2Cl)c2nc(N)[nH]c2c1 Show InChI InChI=1S/C14H11Cl2N3/c1-7-5-9(8-3-2-4-10(15)12(8)16)13-11(6-7)18-14(17)19-13/h2-6H,1H3,(H3,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...				ACS Med Chem Lett 11: 358-364 (2020) Article DOI: 10.1021/acsmedchemlett.9b00420
					More data for this Ligand-Target Pair