BDBM50511462 CHEMBL4575540

SMILES: Cc1cccc(c1C)-c1nc(NS(C)(=O)=O)cc2NCCCc12

InChI Key: InChIKey=GLMQIIJYKOFTBX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50511462   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
7,8-dihydro-8-oxoguanine triphosphatase (Homo sapiens (Human))	BDBM50511462 (CHEMBL4575540) Show SMILES Cc1cccc(c1C)-c1nc(NS(C)(=O)=O)cc2NCCCc12 Show InChI InChI=1S/C17H21N3O2S/c1-11-6-4-7-13(12(11)2)17-14-8-5-9-18-15(14)10-16(19-17)20-23(3,21)22/h4,6-7,10,18H,5,8-9H2,1-3H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	773	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...				ACS Med Chem Lett 11: 358-364 (2020) Article DOI: 10.1021/acsmedchemlett.9b00420
					More data for this Ligand-Target Pair