null
SMILES: C[C@@H](COc1ccccc1)COc1ccn(-c2cccc(C)c2)c(=O)c1
InChI Key: InChIKey=KIHWPJLHBQPIHX-SFHVURJKSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat)) | BDBM50512696 (CHEMBL4519557) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux | Bioorg Med Chem Lett 29: 2670-2674 (2019) Article DOI: 10.1016/j.bmcl.2019.07.030 BindingDB Entry DOI: 10.7270/Q2KP85HM | |||||||||||
More data for this Ligand-Target Pair |