BDBM50512885 CHEMBL4441003

SMILES: C[C@H](Nc1ncnc2[nH]cc(-c3cccc(NS(C)(=O)=O)c3)c12)c1nc2cccc(C)c2c(=O)n1-c1ccccc1

InChI Key: InChIKey=WPXJKSSUCNBXGY-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50512885 (CHEMBL4441003) Show SMILES C[C@H](Nc1ncnc2[nH]cc(-c3cccc(NS(C)(=O)=O)c3)c12)c1nc2cccc(C)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C30H27N7O3S/c1-18-9-7-14-24-25(18)30(38)37(22-12-5-4-6-13-22)29(35-24)19(2)34-28-26-23(16-31-27(26)32-17-33-28)20-10-8-11-21(15-20)36-41(3,39)40/h4-17,19,36H,1-3H3,(H2,31,32,33,34)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) preincubated for 30 mins followed by insulin stimulation for 5 mins by Western blot analysis				J Med Chem 62: 4783-4814 (2019) Article DOI: 10.1021/acs.jmedchem.8b01298
					More data for this Ligand-Target Pair