BDBM50513574 CHEMBL4539722

SMILES: Clc1cc(cnc1Cl)\N=C\c1ccc2[nH]ncc2c1

InChI Key: InChIKey=URIFNKZDEQYIEQ-FZSIALSZSA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50513574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50513574 (CHEMBL4539722) Show SMILES Clc1cc(cnc1Cl)\N=C\c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C13H8Cl2N4/c14-11-4-10(7-17-13(11)15)16-5-8-1-2-12-9(3-8)6-18-19-12/h1-7H,(H,18,19)/b16-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NTZ Lab Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...				Eur J Med Chem 179: 404-422 (2019) Article DOI: 10.1016/j.ejmech.2019.06.041
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50513574 (CHEMBL4539722) Show SMILES Clc1cc(cnc1Cl)\N=C\c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C13H8Cl2N4/c14-11-4-10(7-17-13(11)15)16-5-8-1-2-12-9(3-8)6-18-19-12/h1-7H,(H,18,19)/b16-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
NTZ Lab Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...				Eur J Med Chem 179: 404-422 (2019) Article DOI: 10.1016/j.ejmech.2019.06.041
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50513574 (CHEMBL4539722) Show SMILES Clc1cc(cnc1Cl)\N=C\c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C13H8Cl2N4/c14-11-4-10(7-17-13(11)15)16-5-8-1-2-12-9(3-8)6-18-19-12/h1-7H,(H,18,19)/b16-5+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NTZ Lab Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...				Eur J Med Chem 179: 404-422 (2019) Article DOI: 10.1016/j.ejmech.2019.06.041
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50513574 (CHEMBL4539722) Show SMILES Clc1cc(cnc1Cl)\N=C\c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C13H8Cl2N4/c14-11-4-10(7-17-13(11)15)16-5-8-1-2-12-9(3-8)6-18-19-12/h1-7H,(H,18,19)/b16-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
NTZ Lab Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...				Eur J Med Chem 179: 404-422 (2019) Article DOI: 10.1016/j.ejmech.2019.06.041
					More data for this Ligand-Target Pair