BDBM50514066 CHEMBL4589217

SMILES: CC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCS(C)(=O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C=O

InChI Key: InChIKey=GJRWZZORZFKXQE-BIHRQFPBSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen (Homo sapiens (Human))	BDBM50514066 (CHEMBL4589217) Show SMILES CC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCS(C)(=O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C=O |r| Show InChI InChI=1S/C28H46N8O8S/c1-18(38)33-22(7-3-4-13-29)25(40)35-23(12-15-45(2,43)44)26(41)36-24(16-19-8-10-21(39)11-9-19)27(42)34-20(17-37)6-5-14-32-28(30)31/h8-11,17,20,22-24,39H,3-7,12-16,29H2,1-2H3,(H,33,38)(H,34,42)(H,35,40)(H,36,41)(H4,30,31,32)/t20-,22-,23-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of human plasmin assessed as reduction in proteolysis activity in presence of fibrinogen after 90 mins by SDS-PAGE analysis				J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060
					More data for this Ligand-Target Pair