BDBM50514109 CHEMBL4519616

SMILES: CC(C)c1cc(nc(N)n1)N1CC(C1)N(C)C

InChI Key: InChIKey=YPBPWSIJZRPMHU-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50514109 (CHEMBL4519616) Show SMILES CC(C)c1cc(nc(N)n1)N1CC(C1)N(C)C Show InChI InChI=1S/C12H21N5/c1-8(2)10-5-11(15-12(13)14-10)17-6-9(7-17)16(3)4/h5,8-9H,6-7H2,1-4H3,(H2,13,14,15)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]NAMH from human H3R expressed in HEK293T cells incubated for 2 hrs by microbeta scintillation counting analysis				J Med Chem 62: 10848-10866 (2019) Article DOI: 10.1021/acs.jmedchem.9b01462
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50514109 (CHEMBL4519616) Show SMILES CC(C)c1cc(nc(N)n1)N1CC(C1)N(C)C Show InChI InChI=1S/C12H21N5/c1-8(2)10-5-11(15-12(13)14-10)17-6-9(7-17)16(3)4/h5,8-9H,6-7H2,1-4H3,(H2,13,14,15)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Vrije Universiteit Amsterdam Curated by ChEMBL					Assay Description Agonist activity at human H3R expressed on HEK293T cells assessed as inhibition of forskolin-induced CRE-driven luciferase activity co-incubated with...				J Med Chem 62: 10848-10866 (2019) Article DOI: 10.1021/acs.jmedchem.9b01462
					More data for this Ligand-Target Pair