BDBM50514412 CHEMBL4462216

SMILES: OC(=O)c1nonc1NCn1nnnc1-c1ccccc1

InChI Key: InChIKey=QOGXHCFJYHJJON-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514412   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor STAT5b (STAT5b) (Homo sapiens (Human))	BDBM50514412 (CHEMBL4462216) Show SMILES OC(=O)c1nonc1NCn1nnnc1-c1ccccc1 Show InChI InChI=1S/C11H9N7O3/c19-11(20)8-9(15-21-14-8)12-6-18-10(13-16-17-18)7-4-2-1-3-5-7/h1-5H,6H2,(H,12,15)(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...				J Med Chem 63: 3817-3833 (2020) Article DOI: 10.1021/acs.jmedchem.9b01183
					More data for this Ligand-Target Pair