BDBM50515598 CHEMBL4526049
SMILES: COc1cc(N)c(Cl)cc1C(=O)CCC1CCN(Cc2ccc(O)c(O)c2)CC1
InChI Key: InChIKey=WJKHUZSNGGHVOF-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Serotonin (5-HT) receptor (Homo sapiens (Human)) | BDBM50515598 (CHEMBL4526049) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Normandie Univ Curated by ChEMBL | Assay Description Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50515598 (CHEMBL4526049) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 138 | n/a | n/a | n/a | n/a | n/a | n/a |
Normandie Univ Curated by ChEMBL | Assay Description Inhibition of human erythrocytes AChE assessed as reduction in 5-thio-2-nitrobenzoate anion formation using acetylthiocholine iodide as substrate pre... | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (Homo sapiens (Human)) | BDBM50515598 (CHEMBL4526049) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a |
Normandie Univ Curated by ChEMBL | Assay Description Partial agonist activity at human HA-tagged 5HT4 receptor expressed in COS7 cells assessed as induction of cAMP production measured after 10 mins by ... | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (Homo sapiens (Human)) | BDBM50515598 (CHEMBL4526049) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Normandie Univ Curated by ChEMBL | Assay Description Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 | |||||||||||
More data for this Ligand-Target Pair |