null

SMILES: Cl.NC[C@H]1C[C@]1(F)c1cccc(F)c1

InChI Key: InChIKey=WWBXYAHFUIPNKA-SCYNACPDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50515731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50515731 (CHEMBL4466591) Show SMILES Cl.NC[C@H]1C[C@]1(F)c1cccc(F)c1 |r| Show InChI InChI=1S/C10H11F2N.ClH/c11-9-3-1-2-7(4-9)10(12)5-8(10)6-13;/h1-4,8H,5-6,13H2;1H/t8-,10+;/m1./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.80	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human unedited 5HT2C receptor isoform INI expressed in Flp-In-293 cells assessed as increase in calcium influx measur...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111626
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50515731 (CHEMBL4466591) Show SMILES Cl.NC[C@H]1C[C@]1(F)c1cccc(F)c1 |r| Show InChI InChI=1S/C10H11F2N.ClH/c11-9-3-1-2-7(4-9)10(12)5-8(10)6-13;/h1-4,8H,5-6,13H2;1H/t8-,10+;/m1./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human unedited 5HT2C receptor isoform INI expressed in Flp-In-293 cells assessed as increase in calcium influx measur...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111626
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50515731 (CHEMBL4466591) Show SMILES Cl.NC[C@H]1C[C@]1(F)c1cccc(F)c1 |r| Show InChI InChI=1S/C10H11F2N.ClH/c11-9-3-1-2-7(4-9)10(12)5-8(10)6-13;/h1-4,8H,5-6,13H2;1H/t8-,10+;/m1./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as increase in calcium influx measured for 300 secs by Fl...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111626
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50515731 (CHEMBL4466591) Show SMILES Cl.NC[C@H]1C[C@]1(F)c1cccc(F)c1 |r| Show InChI InChI=1S/C10H11F2N.ClH/c11-9-3-1-2-7(4-9)10(12)5-8(10)6-13;/h1-4,8H,5-6,13H2;1H/t8-,10+;/m1./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as increase in calcium influx measured for 300 secs by Fl...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111626
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50515731 (CHEMBL4466591) Show SMILES Cl.NC[C@H]1C[C@]1(F)c1cccc(F)c1 |r| Show InChI InChI=1S/C10H11F2N.ClH/c11-9-3-1-2-7(4-9)10(12)5-8(10)6-13;/h1-4,8H,5-6,13H2;1H/t8-,10+;/m1./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as increase in calcium influx measured for 300 secs by Fl...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111626
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50515731 (CHEMBL4466591) Show SMILES Cl.NC[C@H]1C[C@]1(F)c1cccc(F)c1 |r| Show InChI InChI=1S/C10H11F2N.ClH/c11-9-3-1-2-7(4-9)10(12)5-8(10)6-13;/h1-4,8H,5-6,13H2;1H/t8-,10+;/m1./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as increase in calcium influx measured for 300 secs by Fl...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111626
					More data for this Ligand-Target Pair