BDBM50515796 CHEMBL4548151

SMILES: Cc1nnc2CCC(Nc3ccc(Cl)cc3)c3cc(ccc3-n12)-c1cnc(N)nc1

InChI Key: InChIKey=BSFILPZIPHRPKR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50515796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50515796 (CHEMBL4548151) Show SMILES Cc1nnc2CCC(Nc3ccc(Cl)cc3)c3cc(ccc3-n12)-c1cnc(N)nc1 Show InChI InChI=1S/C22H20ClN7/c1-13-28-29-21-9-7-19(27-17-5-3-16(23)4-6-17)18-10-14(2-8-20(18)30(13)21)15-11-25-22(24)26-12-15/h2-6,8,10-12,19,27H,7,9H2,1H3,(H2,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity to human recombinant BRD4 BD2 (333 to 460 residues) by fluorescence polarization assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111633
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50515796 (CHEMBL4548151) Show SMILES Cc1nnc2CCC(Nc3ccc(Cl)cc3)c3cc(ccc3-n12)-c1cnc(N)nc1 Show InChI InChI=1S/C22H20ClN7/c1-13-28-29-21-9-7-19(27-17-5-3-16(23)4-6-17)18-10-14(2-8-20(18)30(13)21)15-11-25-22(24)26-12-15/h2-6,8,10-12,19,27H,7,9H2,1H3,(H2,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	726	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity to human recombinant BRD4 BD1 (44 to 168 residues) by fluorescence polarization assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111633
					More data for this Ligand-Target Pair