BDBM50516140 CHEMBL4550900

SMILES: COc1ccc(NC(=O)[C@H]2CCN([C@H](C)C2)c2ncccc2Br)cc1Cl

InChI Key: InChIKey=HZCJWMYCYMDXPI-OLZOCXBDSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50516140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human))	BDBM50516140 (CHEMBL4550900) Show SMILES COc1ccc(NC(=O)[C@H]2CCN([C@H](C)C2)c2ncccc2Br)cc1Cl |r| Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)/t12-,13+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743
					More data for this Ligand-Target Pair