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SMILES: COc1ccc(Oc2nc(Nc3ccc(cc3)-c3nnn[nH]3)ncc2Cl)cc1

InChI Key: InChIKey=SABABAUUBNVNGG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50516344   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50516344
PNG
(CHEMBL4462759)
Show SMILES COc1ccc(Oc2nc(Nc3ccc(cc3)-c3nnn[nH]3)ncc2Cl)cc1
Show InChI InChI=1S/C18H14ClN7O2/c1-27-13-6-8-14(9-7-13)28-17-15(19)10-20-18(22-17)21-12-4-2-11(3-5-12)16-23-25-26-24-16/h2-10H,1H3,(H,20,21,22)(H,23,24,25,26)
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PC cid
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Article
PubMed
n/an/a 0.0120n/an/an/an/an/an/a



Henan University of Chinese Medicine

Curated by ChEMBL


Assay Description
Inhibition of Aurora A (unknown origin)

Eur J Med Chem 178: 341-351 (2019)


Article DOI: 10.1016/j.ejmech.2019.05.071
More data for this
Ligand-Target Pair