BDBM50517126 CHEMBL4463797

SMILES: CCCCN(C(C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2ccccc2o1

InChI Key: InChIKey=XEHFWPJFUYLUSK-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50517126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50517126 (CHEMBL4463797) Show SMILES CCCCN(C(C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2ccccc2o1 Show InChI InChI=1S/C26H26N6O/c1-3-4-17-32(26-27-23-11-7-8-12-24(23)33-26)18(2)19-13-15-20(16-14-19)21-9-5-6-10-22(21)25-28-30-31-29-25/h5-16,18H,3-4,17H2,1-2H3,(H,28,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Kirin Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of CXCR4 expressed in human CAL1 cells assessed as reduction in SDF1alpha-induced intracellular calcium ion concentration preincubated for...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115091
					More data for this Ligand-Target Pair
G-protein coupled receptor ChemR23 (Homo sapiens (Human))	BDBM50517126 (CHEMBL4463797) Show SMILES CCCCN(C(C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2ccccc2o1 Show InChI InChI=1S/C26H26N6O/c1-3-4-17-32(26-27-23-11-7-8-12-24(23)33-26)18(2)19-13-15-20(16-14-19)21-9-5-6-10-22(21)25-28-30-31-29-25/h5-16,18H,3-4,17H2,1-2H3,(H,28,29,30,31)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
Kyowa Kirin Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115091
					More data for this Ligand-Target Pair
G-protein coupled receptor ChemR23 (Homo sapiens (Human))	BDBM50517126 (CHEMBL4463797) Show SMILES CCCCN(C(C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2ccccc2o1 Show InChI InChI=1S/C26H26N6O/c1-3-4-17-32(26-27-23-11-7-8-12-24(23)33-26)18(2)19-13-15-20(16-14-19)21-9-5-6-10-22(21)25-28-30-31-29-25/h5-16,18H,3-4,17H2,1-2H3,(H,28,29,30,31)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Kirin Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of chemR23 in human CAL1 cells assessed as reduction in chemerin-induced intracellular calcium ion concentration preincubated for 45 mins ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115091
					More data for this Ligand-Target Pair