BDBM50517138 CHEMBL4557657

SMILES: CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2cc(NC(=O)NC)ccc2o1

InChI Key: InChIKey=BMVNOIQEOAAUNH-GOSISDBHSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50517138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor ChemR23 (Homo sapiens (Human))	BDBM50517138 (CHEMBL4557657) Show SMILES CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2cc(NC(=O)NC)ccc2o1 |r| Show InChI InChI=1S/C28H30N8O2/c1-4-5-16-36(28-31-24-17-21(30-27(37)29-3)14-15-25(24)38-28)18(2)19-10-12-20(13-11-19)22-8-6-7-9-23(22)26-32-34-35-33-26/h6-15,17-18H,4-5,16H2,1-3H3,(H2,29,30,37)(H,32,33,34,35)/t18-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Kirin Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of chemR23 in human CAL1 cells assessed as reduction in chemerin-induced intracellular calcium ion concentration preincubated for 45 mins ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115091
					More data for this Ligand-Target Pair
G-protein coupled receptor ChemR23 (Homo sapiens (Human))	BDBM50517138 (CHEMBL4557657) Show SMILES CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2cc(NC(=O)NC)ccc2o1 |r| Show InChI InChI=1S/C28H30N8O2/c1-4-5-16-36(28-31-24-17-21(30-27(37)29-3)14-15-25(24)38-28)18(2)19-10-12-20(13-11-19)22-8-6-7-9-23(22)26-32-34-35-33-26/h6-15,17-18H,4-5,16H2,1-3H3,(H2,29,30,37)(H,32,33,34,35)/t18-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	940	n/a	n/a	n/a	n/a
Kyowa Kirin Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115091
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50517138 (CHEMBL4557657) Show SMILES CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2cc(NC(=O)NC)ccc2o1 |r| Show InChI InChI=1S/C28H30N8O2/c1-4-5-16-36(28-31-24-17-21(30-27(37)29-3)14-15-25(24)38-28)18(2)19-10-12-20(13-11-19)22-8-6-7-9-23(22)26-32-34-35-33-26/h6-15,17-18H,4-5,16H2,1-3H3,(H2,29,30,37)(H,32,33,34,35)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Kirin Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of CXCR4 expressed in human CAL1 cells assessed as reduction in SDF1alpha-induced intracellular calcium ion concentration preincubated for...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115091
					More data for this Ligand-Target Pair
Chemokine-like receptor 1 (Mus musculus)	BDBM50517138 (CHEMBL4557657) Show SMILES CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2cc(NC(=O)NC)ccc2o1 |r| Show InChI InChI=1S/C28H30N8O2/c1-4-5-16-36(28-31-24-17-21(30-27(37)29-3)14-15-25(24)38-28)18(2)19-10-12-20(13-11-19)22-8-6-7-9-23(22)26-32-34-35-33-26/h6-15,17-18H,4-5,16H2,1-3H3,(H2,29,30,37)(H,32,33,34,35)/t18-/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Kirin Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of chemR23 expressed in mouse BA/F3 cells assessed as reduction in chemerin-induced intracellular calcium ion concentration preincubated f...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115091
					More data for this Ligand-Target Pair