BDBM50517151 CHEMBL4467290

SMILES: CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2ccccc2o1

InChI Key: InChIKey=XEHFWPJFUYLUSK-GOSISDBHSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50517151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor ChemR23 (Homo sapiens (Human))	BDBM50517151 (CHEMBL4467290) Show SMILES CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2ccccc2o1 |r| Show InChI InChI=1S/C26H26N6O/c1-3-4-17-32(26-27-23-11-7-8-12-24(23)33-26)18(2)19-13-15-20(16-14-19)21-9-5-6-10-22(21)25-28-30-31-29-25/h5-16,18H,3-4,17H2,1-2H3,(H,28,29,30,31)/t18-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Kyowa Kirin Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115091
					More data for this Ligand-Target Pair
Chemokine-like receptor 1 (Mus musculus)	BDBM50517151 (CHEMBL4467290) Show SMILES CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2ccccc2o1 |r| Show InChI InChI=1S/C26H26N6O/c1-3-4-17-32(26-27-23-11-7-8-12-24(23)33-26)18(2)19-13-15-20(16-14-19)21-9-5-6-10-22(21)25-28-30-31-29-25/h5-16,18H,3-4,17H2,1-2H3,(H,28,29,30,31)/t18-/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Kirin Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of chemR23 expressed in mouse BA/F3 cells assessed as reduction in chemerin-induced intracellular calcium ion concentration preincubated f...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115091
					More data for this Ligand-Target Pair
G-protein coupled receptor ChemR23 (Homo sapiens (Human))	BDBM50517151 (CHEMBL4467290) Show SMILES CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2ccccc2o1 |r| Show InChI InChI=1S/C26H26N6O/c1-3-4-17-32(26-27-23-11-7-8-12-24(23)33-26)18(2)19-13-15-20(16-14-19)21-9-5-6-10-22(21)25-28-30-31-29-25/h5-16,18H,3-4,17H2,1-2H3,(H,28,29,30,31)/t18-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50517151 (CHEMBL4467290) Show SMILES CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2ccccc2o1 |r| Show InChI InChI=1S/C26H26N6O/c1-3-4-17-32(26-27-23-11-7-8-12-24(23)33-26)18(2)19-13-15-20(16-14-19)21-9-5-6-10-22(21)25-28-30-31-29-25/h5-16,18H,3-4,17H2,1-2H3,(H,28,29,30,31)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Kirin Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of CXCR4 expressed in human CAL1 cells assessed as reduction in SDF1alpha-induced intracellular calcium ion concentration preincubated for...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115091
					More data for this Ligand-Target Pair
G-protein coupled receptor ChemR23 (Homo sapiens (Human))	BDBM50517151 (CHEMBL4467290) Show SMILES CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2ccccc2o1 |r| Show InChI InChI=1S/C26H26N6O/c1-3-4-17-32(26-27-23-11-7-8-12-24(23)33-26)18(2)19-13-15-20(16-14-19)21-9-5-6-10-22(21)25-28-30-31-29-25/h5-16,18H,3-4,17H2,1-2H3,(H,28,29,30,31)/t18-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Kirin Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of chemR23 in human CAL1 cells assessed as reduction in chemerin-induced intracellular calcium ion concentration preincubated for 45 mins ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115091
					More data for this Ligand-Target Pair