BDBM50517465 CHEMBL4457949

SMILES: Clc1ccc(cc1Cl)-c1ccc(NS(=O)(=O)c2ccccn2)c2ncccc12

InChI Key: InChIKey=IGWZAIMXXMNXQA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glyoxalase I (Homo sapiens (Human))	BDBM50517465 (CHEMBL4457949) Show SMILES Clc1ccc(cc1Cl)-c1ccc(NS(=O)(=O)c2ccccn2)c2ncccc12 Show InChI InChI=1S/C20H13Cl2N3O2S/c21-16-8-6-13(12-17(16)22)14-7-9-18(20-15(14)4-3-11-24-20)25-28(26,27)19-5-1-2-10-23-19/h1-12,25H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...				J Med Chem 62: 1609-1625 (2019) Article DOI: 10.1021/acs.jmedchem.8b01868
					More data for this Ligand-Target Pair