BDBM50517489 CHEMBL4454726

SMILES: Fc1ccc(CCc2cc(NS(=O)(=O)c3ccccn3)c3ncccc3c2)cc1

InChI Key: InChIKey=CAXPYZGXPJSFTF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glyoxalase I (Homo sapiens (Human))	BDBM50517489 (CHEMBL4454726) Show SMILES Fc1ccc(CCc2cc(NS(=O)(=O)c3ccccn3)c3ncccc3c2)cc1 Show InChI InChI=1S/C22H18FN3O2S/c23-19-10-8-16(9-11-19)6-7-17-14-18-4-3-13-25-22(18)20(15-17)26-29(27,28)21-5-1-2-12-24-21/h1-5,8-15,26H,6-7H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...				J Med Chem 62: 1609-1625 (2019) Article DOI: 10.1021/acs.jmedchem.8b01868
					More data for this Ligand-Target Pair