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BDBM50517491 CHEMBL4468778

SMILES: O[C@H]([C@@H](O)C(O)=O)C(O)=O.O=C(NCCN1CCCCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1

InChI Key: InChIKey=SNEOPDNVNBBSDE-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517491   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50517491
PNG
(CHEMBL4468778)
Show SMILES O[C@H]([C@@H](O)C(O)=O)C(O)=O.O=C(NCCN1CCCCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 |r|
Show InChI InChI=1S/C23H35N3O2/c27-23(24-13-18-25-14-2-1-3-15-25)19-7-9-21(10-8-19)28-22-11-16-26(17-12-22)20-5-4-6-20/h7-10,20,22H,1-6,11-18H2,(H,24,27)
Reactome pathway
KEGG

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PC cid
PC sid
UniChem
Article
PubMed
 3.20n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting

J Med Chem 62: 1203-1217 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01280
More data for this
Ligand-Target Pair