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BDBM50517502 CHEMBL4439392

SMILES: O[C@H]([C@@H](O)C(O)=O)C(O)=O.O=C(CN1CCCCCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1

InChI Key: InChIKey=QHKRLNJNOZHULO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517502   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50517502
PNG
(CHEMBL4439392)
Show SMILES O[C@H]([C@@H](O)C(O)=O)C(O)=O.O=C(CN1CCCCCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 |r|
Show InChI InChI=1S/C23H35N3O2/c27-23(18-25-14-3-1-2-4-15-25)24-19-8-10-21(11-9-19)28-22-12-16-26(17-13-22)20-6-5-7-20/h8-11,20,22H,1-7,12-18H2,(H,24,27)
Reactome pathway
KEGG

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PC cid
PC sid
UniChem
Article
PubMed
 2.60n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting

J Med Chem 62: 1203-1217 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01280
More data for this
Ligand-Target Pair