BDBM50517520 CHEMBL4441571

SMILES: CCN(C(=O)CN1CCOCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1

InChI Key: InChIKey=JRAULUZYXCYHLC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517520 (CHEMBL4441571) Show SMILES CCN(C(=O)CN1CCOCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C23H35N3O3/c1-2-26(23(27)18-24-14-16-28-17-15-24)20-6-8-21(9-7-20)29-22-10-12-25(13-11-22)19-4-3-5-19/h6-9,19,22H,2-5,10-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280
					More data for this Ligand-Target Pair