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BDBM50517522 CHEMBL4534815

SMILES: C[C@@H]1CCCN1CC(=O)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1

InChI Key: InChIKey=LBOYXLZIWDFAQX-QGZVFWFLSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517522   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50517522
PNG
(CHEMBL4534815)
Show SMILES C[C@@H]1CCCN1CC(=O)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 |r|
Show InChI InChI=1S/C22H33N3O2/c1-17-4-3-13-25(17)16-22(26)23-18-7-9-20(10-8-18)27-21-11-14-24(15-12-21)19-5-2-6-19/h7-10,17,19,21H,2-6,11-16H2,1H3,(H,23,26)/t17-/m1/s1
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Article
PubMed
 2.60n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting

J Med Chem 62: 1203-1217 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01280
More data for this
Ligand-Target Pair