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BDBM50517534 CHEMBL4476066

SMILES: Cl.Cl.CCOC(=O)N1CCN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2)CC1

InChI Key: InChIKey=CKLSPWWABAQKRY-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517534   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50517534
PNG
(CHEMBL4476066)
Show SMILES Cl.Cl.CCOC(=O)N1CCN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2)CC1
Show InChI InChI=1S/C24H36N4O4/c1-2-31-24(30)28-16-14-26(15-17-28)18-23(29)25-19-6-8-21(9-7-19)32-22-10-12-27(13-11-22)20-4-3-5-20/h6-9,20,22H,2-5,10-18H2,1H3,(H,25,29)
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Article
PubMed
 1.10n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting

J Med Chem 62: 1203-1217 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01280
More data for this
Ligand-Target Pair