BDBM50517772 CHEMBL4568408

SMILES: COc1cc(\C=C\C(=O)c2ccc(NC(=O)c3cc4cc5cc(C)ccc5nc4s3)cc2)cc(OC)c1OC

InChI Key: InChIKey=UWIYEYRJJQXAOU-WUXMJOGZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517772   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50517772 (CHEMBL4568408) Show SMILES COc1cc(\C=C\C(=O)c2ccc(NC(=O)c3cc4cc5cc(C)ccc5nc4s3)cc2)cc(OC)c1OC Show InChI InChI=1S/C31H26N2O5S/c1-18-5-11-24-21(13-18)16-22-17-28(39-31(22)33-24)30(35)32-23-9-7-20(8-10-23)25(34)12-6-19-14-26(36-2)29(38-4)27(15-19)37-3/h5-17H,1-4H3,(H,32,35)/b12-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...				Bioorg Med Chem 27: 1076-1086 (2019) Article DOI: 10.1016/j.bmc.2019.02.012
					More data for this Ligand-Target Pair