BDBM50517836 CHEMBL4542143

SMILES: Clc1ccc(cc1)-c1cn2cc(ccc2n1)-c1cccc(CN2CCOCC2)c1

InChI Key: InChIKey=VEYDXOOCZJBSDO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517836   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517836 (CHEMBL4542143) Show SMILES Clc1ccc(cc1)-c1cn2cc(ccc2n1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C24H22ClN3O/c25-22-7-4-19(5-8-22)23-17-28-16-21(6-9-24(28)26-23)20-3-1-2-18(14-20)15-27-10-12-29-13-11-27/h1-9,14,16-17H,10-13,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024
					More data for this Ligand-Target Pair