BDBM50517974 CHEMBL4457733

SMILES: COc1cc2c(Oc3ccc(NS(=O)(=O)c4cc(F)ccc4F)cc3F)ccnc2cc1OCCCN1CCCC(C)C1

InChI Key: InChIKey=UFFFDUINWKEBCZ-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50517974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50517974 (CHEMBL4457733) Show SMILES COc1cc2c(Oc3ccc(NS(=O)(=O)c4cc(F)ccc4F)cc3F)ccnc2cc1OCCCN1CCCC(C)C1 Show InChI InChI=1S/C31H32F3N3O5S/c1-20-5-3-12-37(19-20)13-4-14-41-30-18-26-23(17-29(30)40-2)27(10-11-35-26)42-28-9-7-22(16-25(28)34)36-43(38,39)31-15-21(32)6-8-24(31)33/h6-11,15-18,20,36H,3-5,12-14,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Vichem Chemie Research Ltd. Curated by ChEMBL					Assay Description Inhibition of AXL (unknown origin) phosphorylation after 1 hr by ELISA				J Med Chem 61: 6277-6292 (2018) Article DOI: 10.1021/acs.jmedchem.8b00672
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50517974 (CHEMBL4457733) Show SMILES COc1cc2c(Oc3ccc(NS(=O)(=O)c4cc(F)ccc4F)cc3F)ccnc2cc1OCCCN1CCCC(C)C1 Show InChI InChI=1S/C31H32F3N3O5S/c1-20-5-3-12-37(19-20)13-4-14-41-30-18-26-23(17-29(30)40-2)27(10-11-35-26)42-28-9-7-22(16-25(28)34)36-43(38,39)31-15-21(32)6-8-24(31)33/h6-11,15-18,20,36H,3-5,12-14,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Vichem Chemie Research Ltd. Curated by ChEMBL					Assay Description Inhibition of AXL (unknown origin)				J Med Chem 61: 6277-6292 (2018) Article DOI: 10.1021/acs.jmedchem.8b00672
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50517974 (CHEMBL4457733) Show SMILES COc1cc2c(Oc3ccc(NS(=O)(=O)c4cc(F)ccc4F)cc3F)ccnc2cc1OCCCN1CCCC(C)C1 Show InChI InChI=1S/C31H32F3N3O5S/c1-20-5-3-12-37(19-20)13-4-14-41-30-18-26-23(17-29(30)40-2)27(10-11-35-26)42-28-9-7-22(16-25(28)34)36-43(38,39)31-15-21(32)6-8-24(31)33/h6-11,15-18,20,36H,3-5,12-14,19H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vichem Chemie Research Ltd. Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin)				J Med Chem 61: 6277-6292 (2018) Article DOI: 10.1021/acs.jmedchem.8b00672
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50517974 (CHEMBL4457733) Show SMILES COc1cc2c(Oc3ccc(NS(=O)(=O)c4cc(F)ccc4F)cc3F)ccnc2cc1OCCCN1CCCC(C)C1 Show InChI InChI=1S/C31H32F3N3O5S/c1-20-5-3-12-37(19-20)13-4-14-41-30-18-26-23(17-29(30)40-2)27(10-11-35-26)42-28-9-7-22(16-25(28)34)36-43(38,39)31-15-21(32)6-8-24(31)33/h6-11,15-18,20,36H,3-5,12-14,19H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vichem Chemie Research Ltd. Curated by ChEMBL					Assay Description Inhibition of c-MET (unknown origin)				J Med Chem 61: 6277-6292 (2018) Article DOI: 10.1021/acs.jmedchem.8b00672
					More data for this Ligand-Target Pair
Calmodulin/Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50517974 (CHEMBL4457733) Show SMILES COc1cc2c(Oc3ccc(NS(=O)(=O)c4cc(F)ccc4F)cc3F)ccnc2cc1OCCCN1CCCC(C)C1 Show InChI InChI=1S/C31H32F3N3O5S/c1-20-5-3-12-37(19-20)13-4-14-41-30-18-26-23(17-29(30)40-2)27(10-11-35-26)42-28-9-7-22(16-25(28)34)36-43(38,39)31-15-21(32)6-8-24(31)33/h6-11,15-18,20,36H,3-5,12-14,19H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
Vichem Chemie Research Ltd. Curated by ChEMBL					Assay Description Inhibition of SRC (unknown origin)				J Med Chem 61: 6277-6292 (2018) Article DOI: 10.1021/acs.jmedchem.8b00672
					More data for this Ligand-Target Pair