BDBM50518400 CHEMBL4447898

SMILES: Nc1ncnc2c(csc12)C(=O)Nc1cccc2n(CC3CCCCC3)nc(Br)c12

InChI Key: InChIKey=HVWAKTUCDXJJME-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50518400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50518400 (CHEMBL4447898) Show SMILES Nc1ncnc2c(csc12)C(=O)Nc1cccc2n(CC3CCCCC3)nc(Br)c12 Show InChI InChI=1S/C21H21BrN6OS/c22-19-16-14(26-21(29)13-10-30-18-17(13)24-11-25-20(18)23)7-4-8-15(16)28(27-19)9-12-5-2-1-3-6-12/h4,7-8,10-12H,1-3,5-6,9H2,(H,26,29)(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Chung-Ang University Curated by ChEMBL					Assay Description Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...				Bioorg Med Chem Lett 29: 271-275 (2019) Article DOI: 10.1016/j.bmcl.2018.11.037
					More data for this Ligand-Target Pair