BDBM50518403 CHEMBL4448250

SMILES: Nc1ncnc2c(csc12)C(=O)Nc1cccc2n(Cc3ccccn3)nc(Br)c12

InChI Key: InChIKey=JQUCADBJPVVWGQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50518403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50518403 (CHEMBL4448250) Show SMILES Nc1ncnc2c(csc12)C(=O)Nc1cccc2n(Cc3ccccn3)nc(Br)c12 Show InChI InChI=1S/C20H14BrN7OS/c21-18-15-13(26-20(29)12-9-30-17-16(12)24-10-25-19(17)22)5-3-6-14(15)28(27-18)8-11-4-1-2-7-23-11/h1-7,9-10H,8H2,(H,26,29)(H2,22,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Chung-Ang University Curated by ChEMBL					Assay Description Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...				Bioorg Med Chem Lett 29: 271-275 (2019) Article DOI: 10.1016/j.bmcl.2018.11.037
					More data for this Ligand-Target Pair