BDBM50518409 CHEMBL4446242

SMILES: Cc1cccc(Cn2nc(C=C)c3c(NC(=O)c4csc5c(N)ncnc45)cccc23)n1

InChI Key: InChIKey=CPKDEYCKULWHRF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50518409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50518409 (CHEMBL4446242) Show SMILES Cc1cccc(Cn2nc(C=C)c3c(NC(=O)c4csc5c(N)ncnc45)cccc23)n1 Show InChI InChI=1S/C23H19N7OS/c1-3-16-19-17(28-23(31)15-11-32-21-20(15)25-12-26-22(21)24)8-5-9-18(19)30(29-16)10-14-7-4-6-13(2)27-14/h3-9,11-12H,1,10H2,2H3,(H,28,31)(H2,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Chung-Ang University Curated by ChEMBL					Assay Description Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...				Bioorg Med Chem Lett 29: 271-275 (2019) Article DOI: 10.1016/j.bmcl.2018.11.037
					More data for this Ligand-Target Pair