BDBM50518410 CHEMBL4446254

SMILES: Nc1ncnc2c(csc12)C(=O)Nc1cccc2n(Cc3cccc(Br)n3)nc(Br)c12

InChI Key: InChIKey=RIRWJJVJXAVNNR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50518410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50518410 (CHEMBL4446254) Show SMILES Nc1ncnc2c(csc12)C(=O)Nc1cccc2n(Cc3cccc(Br)n3)nc(Br)c12 Show InChI InChI=1S/C20H13Br2N7OS/c21-14-6-1-3-10(26-14)7-29-13-5-2-4-12(15(13)18(22)28-29)27-20(30)11-8-31-17-16(11)24-9-25-19(17)23/h1-6,8-9H,7H2,(H,27,30)(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Chung-Ang University Curated by ChEMBL					Assay Description Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...				Bioorg Med Chem Lett 29: 271-275 (2019) Article DOI: 10.1016/j.bmcl.2018.11.037
					More data for this Ligand-Target Pair