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BDBM50518414 CHEMBL4439265

SMILES: CCn1nc(Cn2nc(Br)c3c(NC(=O)c4csc5c(N)ncnc45)cccc23)cc1C(C)C

InChI Key: InChIKey=YXAAIIAVENZISF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50518414   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony stimulating factor receptor


(Homo sapiens (Human))		BDBM50518414
PNG
(CHEMBL4439265)
Show SMILES CCn1nc(Cn2nc(Br)c3c(NC(=O)c4csc5c(N)ncnc45)cccc23)cc1C(C)C
Show InChI InChI=1S/C23H23BrN8OS/c1-4-31-17(12(2)3)8-13(29-31)9-32-16-7-5-6-15(18(16)21(24)30-32)28-23(33)14-10-34-20-19(14)26-11-27-22(20)25/h5-8,10-12H,4,9H2,1-3H3,(H,28,33)(H2,25,26,27)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 19n/an/an/an/an/an/a



Chung-Ang University

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...

Bioorg Med Chem Lett 29: 271-275 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.037
More data for this
Ligand-Target Pair