BDBM50518902 CHEMBL4458011
SMILES: C[C@H](CS)C(=O)N[C@H](B(O)O)c1ccc(C)cc1
InChI Key: InChIKey=JPGSBBIDSWFANO-KOLCDFICSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bacterial beta-lactamase TEM (Escherichia coli) | BDBM50518902 (CHEMBL4458011) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr... | J Med Chem 62: 7160-7184 (2019) Article DOI: 10.1021/acs.jmedchem.9b00735 | |||||||||||
More data for this Ligand-Target Pair |