BDBM50519364 CHEMBL4435700

SMILES: CCN(Cc1ccc(CNC(=O)c2csc3nc[nH]c(=O)c23)cc1)C1CCCCC1

InChI Key: InChIKey=VDWQEXVBMIBDPI-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50519364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
tRNA (guanine-N(1)-)-methyltransferase (Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)	BDBM50519364 (CHEMBL4435700) Show SMILES CCN(Cc1ccc(CNC(=O)c2csc3nc[nH]c(=O)c23)cc1)C1CCCCC1 Show InChI InChI=1S/C23H28N4O2S/c1-2-27(18-6-4-3-5-7-18)13-17-10-8-16(9-11-17)12-24-21(28)19-14-30-23-20(19)22(29)25-15-26-23/h8-11,14-15,18H,2-7,12-13H2,1H3,(H,24,28)(H,25,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Singapore-MIT Alliance for Research and Technology Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa tRNA (guanine(37)-N1)-methyltransferase (Leu5 to Asp25 residues) expressed in Escherichia coli BL21 (DE3) Rosett...				J Med Chem 62: 7788-7805 (2019) Article DOI: 10.1021/acs.jmedchem.9b00582
					More data for this Ligand-Target Pair