BDBM50520449 CHEMBL4459210

SMILES: Clc1cccc(NC(=O)NCc2cnc3scc(C#CC4CC4)n23)c1

InChI Key: InChIKey=HGUDALSVSVZDOY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50520449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50520449 (CHEMBL4459210) Show SMILES Clc1cccc(NC(=O)NCc2cnc3scc(C#CC4CC4)n23)c1 Show InChI InChI=1S/C18H15ClN4OS/c19-13-2-1-3-14(8-13)22-17(24)20-9-16-10-21-18-23(16)15(11-25-18)7-6-12-4-5-12/h1-3,8,10-12H,4-5,9H2,(H2,20,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of recombinant full-length N-terminal His-tagged human IDO1 (1 to 403 residues) expressed in Escherichia coli BL21(DE3) cells				J Med Chem 63: 1642-1659 (2020) Article DOI: 10.1021/acs.jmedchem.9b01549
					More data for this Ligand-Target Pair