BDBM50520847 CHEMBL4467582

SMILES: COc1ccc(Oc2nc(Nc3ccc(cc3)N3CCOCC3)ncc2NC(=O)c2cccc(c2)C(F)(F)F)cc1

InChI Key: InChIKey=GEOVKROBCAHWQW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50520847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Death-associated protein kinase 1 (Homo sapiens (Human))	BDBM50520847 (CHEMBL4467582) Show SMILES COc1ccc(Oc2nc(Nc3ccc(cc3)N3CCOCC3)ncc2NC(=O)c2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C29H26F3N5O4/c1-39-23-9-11-24(12-10-23)41-27-25(35-26(38)19-3-2-4-20(17-19)29(30,31)32)18-33-28(36-27)34-21-5-7-22(8-6-21)37-13-15-40-16-14-37/h2-12,17-18H,13-16H2,1H3,(H,35,38)(H,33,34,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology (KIST) Curated by ChEMBL					Assay Description Inhibition of human DAPK1 (1 to 363 residues) using KKLNRTLSFAEPG as substrate after 120 mins in presence of 10 uM [gamma-33P]-ATP by filtration meth...				Eur J Med Chem 162: 161-175 (2019) Article DOI: 10.1016/j.ejmech.2018.10.057
					More data for this Ligand-Target Pair
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50520847 (CHEMBL4467582) Show SMILES COc1ccc(Oc2nc(Nc3ccc(cc3)N3CCOCC3)ncc2NC(=O)c2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C29H26F3N5O4/c1-39-23-9-11-24(12-10-23)41-27-25(35-26(38)19-3-2-4-20(17-19)29(30,31)32)18-33-28(36-27)34-21-5-7-22(8-6-21)37-13-15-40-16-14-37/h2-12,17-18H,13-16H2,1H3,(H,35,38)(H,33,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology (KIST) Curated by ChEMBL					Assay Description Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate after 120 mins in presence of 10 uM [gamma-33P]-ATP by filtration method				Eur J Med Chem 162: 161-175 (2019) Article DOI: 10.1016/j.ejmech.2018.10.057
					More data for this Ligand-Target Pair